Structural Biology

The effect of drug binding on specific sites in transmembrane helices 4 and 6 of the ABC exporter MsbA studied by DNP-enhanced solid-state NMR #DNPNMR

June 14, 2019 - Spadaccini, Roberta, Hundeep Kaur, Johanna Becker-Baldus, and Clemens Glaubitz. “The Effect of Drug Binding on Specific Sites in Transmembrane Helices 4 and 6 of the ABC Exporter MsbA Studied by DNP-Enhanced Solid-State NMR.

Essential but sparse collagen hydroxylysyl post-translational modifications detected by DNP NMR #DNPNMR

April 15, 2019 - Chow, Wing Ying, Rui Li, Ieva Goldberga, David G. Reid, Rakesh Rajan, Jonathan Clark, Hartmut Oschkinat, Melinda J.

Selective high-resolution DNP-enhanced NMR of biomolecular binding sites #DNPNMR

March 27, 2019 - Marin-Montesinos, Ildefonso, David Goyard, Emilie Gillon, Olivier Renaudet, Anne Imberty, Sabine Hediger, and Gaël De Paëpe.

19F Dynamic Nuclear Polarization at Fast Magic Angle Spinning for NMR of HIV-1 Capsid Protein Assemblies #DNPNMR

March 25, 2019 - This is great work showing off the capabilities of DNP to study 19F in biological samples.

In-Cell NMR: Analysis of Protein–Small Molecule Interactions, Metabolic Processes, and Protein Phosphorylation

March 8, 2019 - Kumar, Amit, Lars Kuhn, and Jochen Balbach. “In-Cell NMR: Analysis of Protein–Small Molecule Interactions, Metabolic Processes, and Protein Phosphorylation.

Hyperpolarized MAS NMR of unfolded and misfolded proteins #DNPNMR

March 4, 2019 - König, Anna, Daniel Schölzel, Boran Uluca, Thibault Viennet, Ümit Akbey, and Henrike Heise. “Hyperpolarized MAS NMR of Unfolded and Misfolded Proteins.

EPR / DNP / NMR Literature Blog