X-Band ODNP Probe

Overhauser Dynamic Nuclear Polarization (ODNP) spectroscopy is a powerful method for site-specific studies of hydration dynamics at or near bio-macromolecules, membrane proteins, or other solid/liquid interfaces. ODNP can be used to enhance the signal intensity in low-field NMR spectroscopy. Bridge12 manufactures ODNP probes so that you can upgrade your EPR spectrometer for ODNP experiments.
Upgrade your existing EPR Spectrometer

Upgrade your existing EPR Spectrometer

Unlike high-field DNP-enhanced solid- state NMR experiments, ODNP experiments at 9 GHz do not require a large superconducting NMR magnet or a high-power/high-frequency microwave source such as a gyrotron. In fact, any X-band EPR spectrometer can be easily upgraded with Bridge12 products for ODNP spectroscopy.

A turn-key ODNP probe for your research

A turn-key ODNP probe for your research

The Bridge12 ODNP probe can be easily installed in a conventional X-band EPR cavity (e.g. Bruker 4102ST or Varian E231) and it comes with all necessary adapter parts to mount the probe. The positions of the NMR coil wires are optimized and the Q of the EPR cavity is only minimally affected. This conserves the high conversion factor of the EPR probe and minimizes sample heating even when using very high microwave power.

Change the sample, not the probe

Change the sample, not the probe

The Bridge12 ODNP probe has a simple and convenient system to change the sample. Once the probe is mounted inside the EPR cavity and its position is optimized the probe will stay inside the EPR cavity and the probe does not have to be removed to change the sample. The sample can be loaded either into a quartz sample tube (2 mm OD, 1 mm ID) or into a small sample capillary (0.84 mm OD, 0.6 mm ID). The probe comes with sample holders for both options.

1H ODNP enhancements of 4-amino TEMPO in WaterObserve 1H or 19F or any nucleus you desire

1H ODNP enhancements of 4-amino TEMPO in WaterObserve 1H or 19F or any nucleus you desire

The Bridge12 ODNP probe is a single channel NMR probe. Depending on your application the probe can be tuned to observe 1H, 19F, 2H, 13C or any other nucleus you are interested in.

1H ODNP Enhancement Profile

1H ODNP Enhancement Profile

All RF tuning elements are conveniently located at the front of the probe. That makes it very easy to tune the probe to a new frequency and for example DNP enhancement profiles are recorded in a very short amount of time.

Technical Specifications

  • Technical Specifications Operating NMR Frequency: 14.5 +/- 0.5 MHz (other frequencies available)
  • Sample Size: Probe works very well with 2 mm sample tubes (Wilmad 712-SQ-250 mm or 0.84 mm capillaries (e.g. VitroCom CV6084-Q)
  • Sample holder and probe mounts included
  • Probe requires EPR cavity, e.g. Bruker 4102ST (TE102), 4119HS, 4122HSQE or ER4123D (TE011-like), or Varian E231 (TE102) for X-Band operation (Other frequencies available)
  • Maximum sample diameter 2.5 mm. Probes for larger sample sizes (non aqueous) are available
  • Unloaded resonator Q with probe installed: > 3100 For optimum performance probe requires flow of clean, dry air (> 5 lpm)

Need More Details?