Postdoc in parahydrogen-enabled MRI/S at the University of Florida

Published: Wednesday, 26 April 2023 - 10:00 -0400

Author: Thorsten Maly

We are seeking a highly motivated postdoctoral associate to join our interdisciplinary team to develop parahydrogen-enabled in-vivo MRI/S at the National High Magnetic Field Lab (NHMFL) at the University of Florida (UF) in Gainesville. Ideally, the candidate would have a background in hyperpolarized NMR/MRI, though candidates with other relevant experience are also encouraged to apply.

The postdoctoral position, available now, is funded by the University of Florida College of Medicine. The University of Florida was recently awarded the NIH NCI (National Cancer Institute) designation.

The research will implement recent advances in the synthesis of hyperpolarized biomolecules in the translation to pre-clinical in-vivo NMR/MRI. The postdoc will join an emerging collaboration among Professors Russ Bowers (UF Chemistry), Austin Evans (UF Chemistry, austinevans@chem.ufl.edu), Chalermchai Khemtong (UF Department of Medicine, Chalermchai.Khemtong@medicine.ufl.edu), and Glenn Walter (UF Department of Physiology and Aging, glennw@ufl.edu), each of whom bring extensive complementary expertise to this project.

The research will employ resources of the Advanced Magnetic Resonance Imaging and Spectroscopy (AMRIS) facility located in the National High Magnetic Field Lab (https://amris.mbi.ufl.edu/), integrating hyperpolarization spin dynamics, MRI pulse sequences, hydrogenation catalysis, chemical synthesis, and chemical separations science. A description of the MRI/S instrumentation available to this project can be viewed at: https://amris.mbi.ufl.edu/mri-systems. In addition, the AMRIS facility equipped with an ARS cryocooler for production of 99% para-enriched hydrogen, various high performance reactor systems (including our patented ultrasonic spray injection reactor, featured in our recent publication, https://doi.org/10.1021/jacs.2c09000) for both heterogeneous and homogeneous hydrogenation. Two dissolution-DNP systems are also available for this research in the AMRIS NHMFL user facility.

https://amris.mbi.ufl.edu/spectrometers-2/silver-600mhz-51mm/

https://amris.mbi.ufl.edu/mri-systems/11t/

We seek to fill the position immediately. To apply, please send your CV to bowers@chem.ufl.edu.

Russ Bowers
Professor of Chemistry & NHMFL Affiliate
2001 Museum Road, University of Florida
Gainesville, Florida 32611

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