Dynamic Nuclear Polarization Enhanced Nuclear Spin Optical Rotation

Published: July 14, 2021

Zhu, Yue, Christian Hilty, and Igor Savukov. “Dynamic Nuclear Polarization Enhanced Nuclear Spin Optical Rotation.” Angewandte Chemie 133, no. 16 (2021): 8905–8.

https://doi.org/10.1002/ange.202016412.

Nuclear spin optical rotation (NSOR) has been investigated as a magneto-optical effect, which holds the potential for applications, including hybrid optical-nuclear magnetic resonance (NMR) spectroscopy and gradientless imaging. The intrinsic nature of NSOR renders its detection relatively insensitive, which has prevented it moving from a proof of concept to a method supporting chemical characterizations. In this work, the dissolution dynamic nuclear polarization technique is introduced to provide nuclear spin polarization, increasing the signal-to-noise ratio by several thousand times. NSOR signals of 1H and 19F nuclei are observed in a single scan for diluted compounds, which has made this effect suitable for the determination of electronic transitions from a specific nucleus in a large molecule.