Postdoctoral Position available in solid-state NMR and DNP in Grenoble (France) ssNMR and DNP investigation of bacterial cell-wall
In this project innovative spectroscopic approaches including solid-state NMR and MAS-DNP will be developed and conducted to investigate the cell wall of mycobacteria and more specifically the role of key peptidoglycan cross-linking enzymes.
This research will fit in a collaborative effort led by two internationally recognized NMR research groups in Grenoble, which covers a wide spectrum of competences going from high-field liquid-state NMR to advanced MAS-DNP. The team directed by Dr Jean-Pierre Simorre in the Biomolecular NMR Spectroscopy group at Institut de Biologie Structurale has a direct access to a state of the art NMR facility containing six high-field spectrometers (950 MHz, 850 MHz, 700 MHz, 3×600 MHz) equipped with latest solid-state NMR and cryogenic liquid-state probes. The DNP group of the Institute for Nanosciences and Cryogenics, directed by Gaël De Paëpe, hosts two 400-MHz MAS-DNP spectrometers (one equipped with a helium-recirculated cooling system) and is a pioneer in instrumentation and methods developments for MAS-DNP.
Applicants are expected to have a doctoral experience in solid-state NMR spectroscopy with a strong interest in biomolecular systems. Knowledge in MAS-DNP will be considered as a plus. The successful candidate will be recruited for 24 months (12 months renewable once) funded by an ANR postdoctoral fellowship. Motivated candidates should send their application with a curriculum vitae, a letter of motivation, and the name of 2 referees by December 31st, 2017 via email to both Jean-Pierre Simorre (firstname.lastname@example.org) and Sabine Hediger (email@example.com).
Selected related publications from our groups:
1. Schanda P, Triboulet S, Laguri C, Bougault CM, Ayala I, Callon M, Arthur M, Simorre JP. (2014) J. Am. Chem. Soc. 136(51):17852-17860.
2. Takahashi H1, Ayala I, Bardet M, De Paëpe G, Simorre JP, Hediger S. (2013) J Am Chem Soc. 135(13):5105-5110.
3. Kern T, Giffard M, Hediger S, Amoroso A, Giustini C, Bui NK, Joris B, Bougault C, Vollmer W, Simorre JP. (2010) J Am Chem Soc. 132(31):10911-10909.
4. Kern T, Hediger S, Müller P, Giustini C, Joris B, Bougault C, Vollmer W, Simorre JP. (2008) J Am Chem Soc. 130(17):5618-5619.
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