[NMR] Postdoc positions in Hyperpolarized 13C MR

Fromt the Ampere Magnetic Resonance List

The University of Maryland School of Medicine has expanded its molecular imaging and interventional research capabilities by establishing the Center for Metabolic Imaging and Therapeutics. The center houses a GE SpinLabTM dynamic nuclear polarizer suitable for preclinical and clinical applications, adjacent to both a new GE 3T 750w MR scanner and an MR Solutions MRS 3017 Preclinical Benchtop MR scanner. The GE MR scanner is also integrated with an Insightec 1024-element high-intensity focused ultrasound (HIFU) system for image-guided interventions (a small-animal 8-element HIFU system by Image Guided Therapy is also available that can be used as a stand-alone unit or interfaced with a Bruker 7T small animal scanner). This expansion is aimed to facilitate both basic science and clinical research by exploring novel molecular imaging agent-based technologies for screening, early disease detection and treatment response, and real-time image-guided interventions.

Multiple postdoctoral research fellowship positions are available in the metabolic imaging group led by Dr. Dirk Mayer. Specific areas of research include optimized acquisition and reconstruction techniques, kinetic modeling for quantitative analysis, and new probe development. These methods will be applied to animal models (e.g., traumatic brain injury, cancer, liver disease) with the eventual goal to translate them to patients. This is an exciting opportunity to work at one of the first sites that will do translational/clinical hyperpolarized 13C MRI/MRS.

The candidate should have a Ph.D. (or equivalent degree) in engineering, physics, physical chemistry, or similar fields. The ideal candidate has a strong background in NMR physics with particular emphasis on in vivo imaging and/or spectroscopy, data acquisition and signal/image processing/analysis. Experience in pulse sequence programming (ideally on GE and/or MR Solutions scanners) is preferred. Knowledge of other computer languages, including C++, Matlab and IDL, and experience in performing small animal imaging is also desirable. Qualified applicants should also have a track record of first-author research papers published in peer-reviewed journals.

Interested individuals should send a letter detailing their research interests, an updated CV and contact information for at least two references Dirk Mayer, Ph.D. (dmayer@som.umaryland.edu).


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