X-Band ODNP Resonator

High-Resolution ODNP Spectroscopy

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Related Product:  X-Band Microwave Source for ODNP

Overhauser DNP Spectroscopy

Overhauser Dynamic Nuclear Polarization (ODNP) enhanced NMR spectroscopy at 9 GHz (0.35 T, 15 MHz 1H NMR frequency) is a powerful method for site-specific studies of hydration dynamics at or near bio-macromolecules, membrane proteins, or other solid/liquid interfaces [1, 2]. In addition ODNP can be used to enhance the signal intensity in low-field NMR spectroscopy. Although the method has been known since the 1960s, it has just recently been successfully applied in structural biology and material science. The unique instrumentation requirements had previously limited the application of ODNP-enhanced NMR spectroscopy, specifically the lack of commercially available microwave sources and DNP resonators.

Upgrade your existing EPR Spectrometer

Unlike high-field DNP-enhanced solid- state NMR experiments, ODNP experiments at 9 GHz do not require a large superconducting NMR magnet or a high-power/high-frequency microwave source such as a gyrotron. In fact, any X-band EPR spectrometer can be easily upgraded with Bridge12 products for ODNP spectroscopy.

A turn-key ODNP resonatorfor your research

The Bridge12 ODNP resonator is compatible with any commercial or home-built X-band EPR spectrometer and can be installed just like any other resonator. The position of the integrated NMR coil is optimized to minimize interference with the microwave electromagnetic fields to achieve a high-Q resonator. This results in a high conversion factor and minimizes sample heating, even when using very high microwave power.

High conversion factor, minimal sample heating

The Bridge12 ODNP resonator is based on a dielectric resonator with a conversion factor > 3 G/√W and a loaded Q > 4000. Little microwave power is required to fully saturate the EPR signal. This is especially important for sample with high dielectric losses (e.g. water), to minimize the microwave induced sample heating. The sample is loaded either into a quartz sample tube (2 mm OD, 1 mm ID) or into a small sample capillary (0.84 mm OD, 0.6 mm ID).

X-Band ODNP spectrum of ethyl crotonate

Observe 1H or 19F or any nucleus you desire

The Bridge12 ODNP resonator has an integrated saddle coil with a single channel NMR circuit. Depending upon your application, the probe can be tuned to observe 1H, 19F, 2H, 13C or any other nucleus you are interested in.

Technical Specifications

  • X-Band Dielectric resonator(unloaded Q ~ 6900)
  • NMR Frequency: 14.5 +/- 0.5 MHz(other frequencies available).
  • Typical pulse length 1 us @ 10 W RF power
  • Maximum Sample Diameter: 2mm
  • Probe requires flow of clean, dry air (> 5 lpm)

Literature

[1] Franck, J.M., et al., Quantitative cw Overhauser Effect Dynamic Nuclear Polarization for The Analysis of Local Water Dynamics, Prog. Nucl. Magn. Reson. Spectrosc., 2013, 74(0), p. 33-56.

[2] Kaminker, I., Barnes, R., Han, Songi, Overhauser Dynamic Nuclear Polarization Studies on Local Water Dynamics, Meth. Enzym., 2015, 564, p. 457-483.

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