Control single-board NMR spectrometers with OpenVnmrJ
Related Product: X-Band Microwave Source for ODNP
Overhauser DNP Spectroscopy
Overhauser enhanced Dynamic Nuclear Polarization (ODNP) spectroscopy in general requires a microwave source, an ODNP resonator and an NMR spectrometer. Low-field ODNP spectroscopy is typically performed at a magnetic field of 0.35 T, corresponding to an NMR frequency of ~15 MHz for protons. While many laboratories rely on home-built ODNP equipment, they often use a commercial (high-field) NMR spectrometer to record the NMR spectrum. However, these spectrometers come with significant overhead and are no cost-effective solutions to ODNP resulting in a large, unnecessary investments.
An ODNP Microwave Source with Integrated NMR Spectrometer
ODNP experiments performed at 0.35 T require an NMR spectrometer operating at 15 MHz to observe protons. A single-board NMR spectrometer such as the RadioProcessor Board (SpinCore Technologies, Inc., Gainesville, FL USA) is a cost-effective solution and sufficient for most ODNP experiments. This integrated NMR spectrometer is now available as an additional option for our Microwave Power Source (Bridge12 MPS).
Many researchers that are interested in ODNP spectroscopy come out of the NMR community but are often unfamiliar with the additional microwave equipment. In collaboration with Open VnmrJ Solutions, the team at Bridge12 Technologies, Inc. has developed a variant of OpenVnmrJ that is tailored towards ODNP spectroscopy to lower the entry barrier.
OpenVnmrJ is the Open Source variant of the highly successful VnmrJ 4.2 acquisition and processing software that many Varian/Agilent NMR users are familiar with. It offers the benefits of a state-of-the-art NMR acquisition and processing software, while maintaining the required flexibility to control auxiliary equipment such as the microwave source. The specific version of OpenVnmrJ and its functions to operate a single-board NMR spectrometer are released as Open Source to make it available to entire research community. OpenVnmrJ is the Open Source version of VnmrJ version 4.2. In 2015, Agilent agreed to transfer the copyright of VnmrJ 4.2 to the University of Oregon. The software is available through the OpenVnmrJ project hosted on GitHub.