Dissolution Dynamic Nuclear Polarization Methodology and Instrumentation #DNPNMR

Kurzbach, Dennis, and Sami Jannin. “Dissolution Dynamic Nuclear Polarization Methodology and Instrumentation,” 7:16, 2018. 


Dissolution dynamic nuclear polarization (d-DNP) denotes a method to enhance signals in nuclear magnetic resonance (NMR) spectroscopy by hyperpolarization of nuclear spins at cryogenic temperature in the solid state prior to a rapid dissolution, transfer of a sample to a conventional NMR spectrometer, and detection at ambient temperatures in the liquid state. The purpose of this chapter is to review the general methodology behind d-DNP, and instrumentational aspects going from basic tasks, such as sample preparation, over operational aspects, such as the use of crosspolarization techniques, magnetic tunnels, and the removal of polarization agents, to future perspectives, such as the long-distance transport of hyperpolarized substrates.

Might this article interest your colleagues? Share it!

Have a question?

If you have questions about our instrumentation or how we can help you, please contact us.